Search results for "shell nacre"

showing 4 items of 4 documents

Evolution of nacre: biochemistry and proteomics of the shell organic matrix of the cephalopod Nautilus macromphalus.

2009

12 pages; International audience; In mollusks, one of the most widely studied shell textures is nacre, the lustrous aragonitic layer that constitutes the internal components of the shells of several bivalves, a few gastropods, and one cephalopod: the nautilus. Nacre contains a minor organic fraction, which displays a wide range of functions in relation to the biomineralization process. Here, we have biochemically characterized the nacre matrix of the cephalopod Nautilus macromphalus. The acid-soluble matrix contains a mixture of polydisperse and discrete proteins and glycoproteins, which interact with the formation of calcite crystals. In addition, a few bind calcium ions. Furthermore, we h…

ProteomeShell (structure)ProteomicsBiochemistryCalcium Carbonate03 medical and health sciencesPaleontologychemistry.chemical_compoundproteomicsevolutionAnimals14. Life underwaterAmino Acid SequenceNautilus[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolecular BiologyChromatography High Pressure Liquid030304 developmental biologyCalciteNautilus macromphalus0303 health sciencesbiology030302 biochemistry & molecular biologyOrganic ChemistryProteinsbiology.organism_classificationbiomineralization[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/BiomaterialsBiological EvolutionCephalopodCalcium carbonatechemistryChemical engineeringSolubilitySpectrometry Mass Matrix-Assisted Laser Desorption-IonizationMolecular MedicineNautilusNautilus macromphalusSequence AlignmentBiomineralizationmollusk shell nacre
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Nacre calcification in the freshwater mussel Unio pictorum: carbonic anhydrase activity and purification of a 95 kDa calcium-binding glycoprotein.

2008

9 pages; International audience; The formation of the molluscan shell is finely tuned by macromolecules of the shell organic matrix. Previous results have shown that the acid-soluble fraction of the nacre matrix of the freshwater paleoheterodont bivalve Unio pictorum shell displays a number of remarkable properties, such as calcium-binding activity, the presence of extensive glycosylations and the capacity to interfere at low concentration with in vitro calcium carbonate precipitation. Here we have found that the nacre-soluble matrix exhibits a carbonic anhydrase activity, an important function in calcification processes. This matrix is composed of three main proteinaceous discrete fraction…

ProteomicsCarbonateschemistry.chemical_elementFresh WaterCalciumBiochemistryMass Spectrometry03 medical and health scienceschemistry.chemical_compoundCalcification PhysiologicCalcium-binding proteinCarbonic anhydraseMollusc shellmedicineAnimalsGlycosyl[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyAmino Acid Sequence[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolecular Biology[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular BiologyCarbonic AnhydrasesGlycoproteins030304 developmental biologychemistry.chemical_classificationbiomineralization; mollusc shell nacre; carbonic anhydrase; 2-DE; two-dimensional electrophoresis; organic matrix0303 health sciencesbiologyCalcium-Binding Proteins030302 biochemistry & molecular biologyOrganic ChemistryUnio pictorumbiology.organism_classificationTrypsin[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/BiomaterialsBivalviaEnzyme ActivationMolecular WeightSolubilitychemistryBiochemistryMicroscopy Electron Scanningbiology.proteinMolecular MedicineCalciumGlycoproteinGelsSequence Analysismedicine.drug
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Deep conservation of bivalve nacre proteins highlighted by shell matrix proteomics of the Unionoida Elliptio complanata and Villosa lienosa.

2016

The formation of the molluscan shell nacre is regulated to a large extent by a matrix of extracellular macromolecules that are secreted by the shell-forming tissue, the mantle. This so-called ‘calcifying matrix’ is a complex mixture of proteins, glycoproteins and polysaccharides that is assembled and occluded within the mineral phase during the calcification process. Better molecular-level characterization of the substances that regulate nacre formation is still required. Notable advances in expressed tag sequencing of freshwater mussels, such as Elliptio complanata and Villosa lienosa , provide a pre-requisite to further characterize bivalve nacre proteins by a proteomic approach. In this…

Unionidae0301 basic medicineUnionoida[ SDV.BA.ZI ] Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyVillosa lienosaBiomedical EngineeringBiophysicsLife Sciences–Earth Science interfaceBioengineeringBiologyProteomicsBiochemistrybivalveEvolution MolecularBiomaterials03 medical and health sciencesPaleontologyCalcification PhysiologicproteomicsAnimal Shells[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]shell nacreShell matrixAnimalscalcium carbonate14. Life underwaterNacreMantle (mollusc)chemistry.chemical_classificationExtracellular Matrix ProteinsElliptiobiology.organism_classificationbiomineralization[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology030104 developmental biologyBiochemistrychemistry[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]organic matrix proteinsGlycoproteinBiotechnologyBiomineralization
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The shell matrix of the freshwater mussel Unio pictorum (Paleoheterodonta, Unionoida). Involvement of acidic polysaccharides from glycoproteins in na…

2007

13 pages; International audience; Among molluscs, the shell biomineralization process is controlled by a set of extracellular macromolecular components secreted by the calcifying mantle. In spite of several studies, these components are mainly known in bivalves from only few members of pteriomorph groups. In the present case, we investigated the biochemical properties of the aragonitic shell of the freshwater bivalve Unio pictorum (Paleoheterodonta, Unionoida). Analysis of the amino acid composition reveals a high amount of glycine, aspartate and alanine in the acid-soluble extract, whereas the acid-insoluble one is rich in alanine and glycine. Monosaccharidic analysis indicates that the in…

glycoproteinMESH: Amino AcidsMESH : PolysaccharidesMESH: BivalviaMESH : Calcification PhysiologicFresh WaterBiochemistryMESH : Spectroscopy Fourier Transform InfraredMESH : BivalviaSpectroscopy Fourier Transform InfraredMollusc shellMESH : Fresh Watercalcium-binding proteinElectrophoresis Gel Two-DimensionalMESH: AnimalsAmino Acidsmollusc shell nacreGel electrophoresisAlanine0303 health sciencesbiologyMESH : Carbohydrates030302 biochemistry & molecular biologyMESH : Extracellular Matrixmatrix macromoleculesExtracellular MatrixBiochemistryMESH: Fresh WaterElectrophoresis Polyacrylamide GelMESH: CarbohydratesFreshwater bivalveCarbohydratesMESH: GlycoproteinsMESH: Extracellular MatrixMESH : Electrophoresis Polyacrylamide GelMESH: Spectroscopy Fourier Transform InfraredMESH: Calcification Physiologic03 medical and health sciencesCalcification PhysiologicPolysaccharidesExtracellularAnimals[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolecular BiologyGlycoproteins030304 developmental biologyMolecular massUnio pictorumMESH : Electrophoresis Gel Two-DimensionalCell Biology[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiology.organism_classificationbiomineralizationMESH: Electrophoresis Gel Two-DimensionalMESH : GlycoproteinsBivalviaIsoelectric pointMESH: PolysaccharidesMESH : Amino AcidsMESH : AnimalsMESH: Electrophoresis Polyacrylamide Gel
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